The Ghent Altarpiece or the Adoration of the Mystic Lamb, by the Van Eyck brothers (1432), is recognised worldwide as a great work of art, and one of the most influential paintings ever made. The work almost reads like an A to Z of Christianity – from the Annunciation to the symbolic sacrifice of Christ, with the ‘Mystic Lamb’ on an altar in a heavenly meadow, bleeding into the Holy Grail. For the first time, this book gathers together diverse insights on the Ghent Altarpiece, the monumental polyptych that the brothers Hubert and Jan van Eyck realised with the assistance of a large workshop and advisers on the painting’s subject matters. This book has the same aim: to bring together experts from the most diverse disciplines. Only by combining the perspectives of (art) historians, philosophers, mathematicians and specialists in optics can one fully understand the riches and depth of this masterpiece.